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These measures reflected the communication and social domains of the diagnostic triad and were to some extent specifically designed to assess ASD.

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Abbreviations ASD autism spectrum disorder ADOS the autism diagnostic. Like all cohort studies, there was significant attrition, and we used multiple imputation to limit any potential bias; however, selection bias related to missing data remains a possibility.

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These developmental periods were selected because of the usual developmental course of autism and because they corresponded to periods that related to some of our key trait measures.

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